-
Brands
View All BrandsAramore® BABOR® Baby Foot® Biocorneum® Biopelle® Clinical Skin® Clinicians Complex® CLn Cool As A Cucumber® Cosmedix® Cyspera® DermaNail® Dermaquest® DermDaughter® EltaMD Emepelle® Glytone HairMax® HigherDose® HydroPeptide® i-On® IMAGE SKINCARE® Institut Esthederm® ISDIN® Jan Marini / Marini SkinSolutions® Jupiter® Keralyt® KYPRIS® Lumara® Luzern® MAKARI® Masktini® MDSolarSciences® Mirabella® NassifMD® Numiere® Nutrafol® Obagi Omnilux® Osmosis® Peter Lamas® Phyla® PMD Beauty® Proscriptix FX® Psoria-Gold® Purpurex® RapidLash® RescueMD® Revision SelpH® Skinbetter Science SkinMedica® Sonoma Pharmaceuticals® Spooge® Style Edit® Tarsum® Teoxane® The Skin Experts® TiZO® Vacation® VERSO® Wallaroo Hat Company® Xtressé Youngblood® ZO® Skin Health
- FSA/HSA
- Promotions
- Locations
- New Arrivals
- Gift Cards
- Perfect Match
$135.00
Unit price perRetinol + PHA Refining Night Cream works overnight to help refine skin texture and tone while reducing the appearance of blemishes, fine lines, and wrinkles for a visibly resurfaced, smoother, clearer, and more even-looking complexion in just 4 weeks*.
Formulated with Entrapped Retinol powered by slow-release technology for optimized delivery into deeper layers of the skin to encourage skin cell turnover, and Polyhydroxy Acid (Gluconolactone) to provide gentle yet effective exfoliation on the surface of the skin, plus eight nourishing ingredients to keep skin hydrated, this overnight cream has the unique ability to help renew and enhance the appearance of your complexion.
Clinically proven to:
- Visibly improve skin smoothness by 29%.*
- Visibly improve skin tone evenness by 10%.*
- Be well-tolerated by the skin.*
*Results based on a 2024 -2025 8-week clinical test. Data on file at Obagi Cosmeceuticals LLC.
RETINOL + PHA REFINING NIGHT CREAM 1.7 fl. oz.
Size: 1.7 fl. oz.
$135.00
Unit price perRetinol + PHA Refining Night Cream works overnight to help refine skin texture and tone while reducing the appearance of blemishes, fine lines, and wrinkles for a visibly resurfaced, smoother, clearer, and more even-looking complexion in just 4 weeks*.
Formulated with Entrapped Retinol powered by slow-release technology for optimized delivery into deeper layers of the skin to encourage skin cell turnover, and Polyhydroxy Acid (Gluconolactone) to provide gentle yet effective exfoliation on the surface of the skin, plus eight nourishing ingredients to keep skin hydrated, this overnight cream has the unique ability to help renew and enhance the appearance of your complexion.
Clinically proven to:
- Visibly improve skin smoothness by 29%.*
- Visibly improve skin tone evenness by 10%.*
- Be well-tolerated by the skin.*
*Results based on a 2024 -2025 8-week clinical test. Data on file at Obagi Cosmeceuticals LLC.
COMPLETE YOUR ROUTINE
Overview
Ingredients
Overview
Overview
Retinol + PHA Refining Night Cream works overnight to help refine skin texture and tone while reducing the appearance of blemishes, fine lines, and wrinkles for a visibly resurfaced, smoother, clearer, and more even-looking complexion in just 4 weeks*.
Formulated with Entrapped Retinol powered by slow-release technology for optimized delivery into deeper layers of the skin to encourage skin cell turnover, and Polyhydroxy Acid (Gluconolactone) to provide gentle yet effective exfoliation on the surface of the skin, plus eight nourishing ingredients to keep skin hydrated, this overnight cream has the unique ability to help renew and enhance the appearance of your complexion.
Clinically proven to:
- Visibly improve skin smoothness by 29%.*
- Visibly improve skin tone evenness by 10%.*
- Be well-tolerated by the skin.*
*Results based on a 2024 -2025 8-week clinical test. Data on file at Obagi Cosmeceuticals LLC.
Ingredients
Ingredients
Retinol
Vitamin E
![{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"anti-aging","bold":true}]}]}](http://advanced-derm-dev.myshopify.com/cdn/shop/files/c1.png?v=1758588868&width=400)
![{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"dry skin","bold":true}]}]}](http://advanced-derm-dev.myshopify.com/cdn/shop/files/c2.png?v=1758588869&width=400)
![{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"dullness","bold":true}]}]}](http://advanced-derm-dev.myshopify.com/cdn/shop/files/c3.png?v=1758588868&width=400)
![{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"sensitive skin","bold":true}]}]}](http://advanced-derm-dev.myshopify.com/cdn/shop/files/c4.png?v=1758588868&width=400)
recommended by
Dermatologist Approved
Recommended by leading dermatologists and skincare professionals worldwide. This clinically-tested formula has been endorsed by medical experts for its safety and efficacy in treating various signs of aging.
Beauty Industry Recognition
Winner of multiple beauty awards and featured in top beauty magazines. Aesthetic practitioners and skincare specialists consistently recommend this product for patients seeking professional-grade anti-aging solutions.
Trusted by Professionals:
Board-certified dermatologists
Aesthetic practitioners
Medical spas
Celebrity estheticians
Skincare specialists
Beauty editors
Clinical researchers
Cosmetic chemists
